La Bête du Gévaudan (Aquatint engraving), 1764.

Wikipedia:

The Beast of Gévaudan [was] the man-eating gray wolf, dog or wolfdog which terrorised the former province of Gévaudan (modern-day département of Lozère and part of Haute-Loire), in the Margeride Mountains in south-central France between 1764 and 1767. The attacks, which covered an area stretching 90 by 80 kilometres (56 by 50 mi), were said to have been committed by a beast or beasts that had formidable teeth and immense tails according to contemporary eyewitnesses.

Victims were often killed by having their throats torn out. The Kingdom of France used a considerable amount of manpower and money to hunt the animals; including the resources of several nobles, soldiers, civilians, and a number of royal huntsmen.

The number of victims differs according to sources. In 1987, one study estimated there had been 210 attacks; resulting in 113 deaths and 49 injuries; 98 of the victims killed were partly eaten. However, other sources claim it killed between 60 to 100 adults and children, as well as injuring more than 30.